What is a key characteristic of autosomal recessive inherited disorders?

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In autosomal recessive inherited disorders, the condition arises when an individual has two copies of a mutated gene, one inherited from each parent. This means that both alleles at the gene locus must be altered for the disorder to manifest. If only one allele is mutated, the individual typically will not show any symptoms of the disease, as the normal allele can often provide sufficient function.

This characteristic underscores the recessive nature of these disorders, requiring both parents to carry at least one copy of the mutated gene, even if they are not affected themselves (as they may each carry one normal allele that compensates for the mutated one). Therefore, in these cases, inherited traits are dependent on the contribution from both parents.

Understanding this allows for better insights into genetic counseling and the risk assessment of passing these conditions to offspring. In contrast, other choices do not accurately describe the nature of autosomal recessive disorders, as the requirement for both gene pairs to be mutated is fundamental to the inheritance pattern of these conditions.

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