What indicates magnesium sulfate toxicity during administration?

Diminished patellar reflexes are a sign of magnesium sulfate toxicity. When magnesium sulfate is administered for conditions such as preeclampsia or eclampsia, it is important to monitor the patient for signs of toxicity. Normally, patellar reflexes are present and responsive; however, as magnesium levels rise in the body, they can lead to neuromuscular depression, which results in a decrease or absence of reflexes.

Monitoring reflexes is a critical component of assessing a patient's status while on magnesium sulfate. The presence of diminished patellar reflexes indicates that the magnesium level may be too high, suggesting that adjustments in treatment or monitoring may be necessary to prevent further complications.

Serum levels above 10 mg/dL can indicate rising magnesium levels, but the clinical picture of diminished reflexes provides a more immediate and practical assessment of toxicity in a patient already receiving the treatment. A severe headache may not directly correspond to magnesium toxicity; it can occur for many other reasons, including hypertension or other stressors. Increased urine output is typically considered a positive sign, as magnesium sulfate can have a diuretic effect, which does not indicate toxicity. Hence, diminished patellar reflexes serve as a reliable clinical indicator for potential magnesium toxicity during