Macrosomic infants are at risk for which of the following conditions?

Macrosomic infants, defined as those born with a birth weight greater than 4,000 grams (or approximately 8 pounds 13 ounces), are indeed at risk for hypoglycemia. This condition occurs because as a fetus grows, it becomes dependent on maternal glucose levels. At birth, if the newborn has been exposed to high levels of glucose in utero due to maternal diabetes (gestational diabetes is a common factor leading to macrosomia), they may experience a rapid drop in blood sugar levels after delivery.

Postnatally, the excess insulin produced in response to high glucose may lead to hypoglycemia once the additional source of glucose is removed. This condition can manifest as lethargy, irritability, poor feeding, or even seizures if not promptly addressed.

In this context, understanding the metabolic adjustments that a macrosomic infant needs to make after birth is crucial. This also emphasizes the importance for healthcare providers to monitor these infants closely for any signs of hypoglycemia, ensuring timely intervention and management to mitigate potential complications.